Figure 6.

Ratio of fluoroquinolone AUC_{0–24 h} in conjunctiva to the MIC₉₀ for methicillin-sensitive S. epidermidis (MSSE) (mITT population).^a

^aMIC₉₀ values were obtained from susceptibility testing of 50 methicillin-sensitive, ciprofloxacin- sensitive S. epidermidis isolates. The values were 0.06 μg/mL for besifloxacin, 0.12 μg/mL for moxifloxacin, and 0.25 μg/mL for gatifloxacin.⁷

Abbreviations: AUC_{0–24 h}, area-under-the-curve, or the total amount of drug delivered to conjunctival tissue in 1 day following 1 dose; mITT, modified intent-to-treat population (N = 108).