Figure 7.

Ratio of fluoroquinolone AUC_{0–24 h} in conjunctiva to the MIC₉₀ for methicillin-resistant S. epidermidis (MRSE) (mITT population).^a

^aMIC₉₀ values were obtained from susceptibility testing of 29 methicillin-resistant, ciprofloxacin-resistant S. epidermidis isolates. The values were 4 μg/mL for besifloxacin, 64 μg/mL for moxifloxacin, and 128 μg/mL for gatifloxacin.²⁴

Abbreviations: AUC_{0–24 h}, area-under-the-curve, or the total amount of drug delivered to conjunctival tissue in 1 day following 1 dose; mITT, modified intent-to-treat population (N = 108).