Table 3.
Tic Effects in TD Subjects (N = 11)
| Rating | Baseline (mean ± SD) | End point (mean ± SD) | Difference (mean ± SD) | Effect size (r) | p value |
|---|---|---|---|---|---|
| CGI-Tic | |||||
| Severity | 4.45 (0.52) | 3.18 (0.60) | −1.27 (0.65) | 0.616 | 0.004 |
| YGTSS | |||||
| Motor tic | 15.82 (4.40) | 9.73 (2.76) | −6.09 (4.41) | 0.598 | 0.005 |
| Vocal tic | 12.36 (7.10) | 7.00 (5.76) | −5.36 (4.57) | 0.569 | 0.008 |
| Total tic | 28.18 (7.74) | 16.73 (7.54) | −11.45 (6.23) | 0.626 | 0.003 |
| Global Severity | 61.82 (13.49) | 33.73 (15.18) | −28.09 (11.83) | 0.626 | 0.003 |
Abbreviations: TD = Tourette's disorder; SD = standard deviation; CGI-Tic = Clinical Global Impressions Scale for tics; YGTSS = Yale Global Tic Severity Scale.