Table 2. WS group shows increased activation to music listening.
Significant clusters of differential activation by group to combined (Upbeat + Downbeat + HB) music conditions versus silent fixation. Positive t-test values indicate activation was greater in the WS group versus TD group; negative t-test values indicate activation was greater in the TD group versus WS group. A cluster threshold of 50 mm3 and a voxel-wise α of 0.005 were used to create the statistical map and resulting regions of interest.
| Hemi- sphere |
Region(s) | Subregion(s) | Brodmann Area |
Cluster Size (mm3) |
Peak Activation | ||||
|---|---|---|---|---|---|---|---|---|---|
| x | y | z | t | p | |||||
| R | Frontal Lobe | Precentral Gyrus | 6 | 108 | 39 | −3 | 44 | 3.85 | 0.0008 |
| R | Frontal Lobe | WM, Precentral Gyrus |
6 | 135 | 32 | 6 | 36 | 3.74 | 0.002 |
| R | Limbic Lobe | Insula | 13 | 1053 | 45 | −35 | 19 | 6.01 | 0.000003 |
| R | Limbic Lobe | Posterior Cingulate | 30 | 135 | 12 | −47 | 6 | 4.30 | 0.0003 |
| R | Temporal Lobe | Superior Temporal Gyrus | 13 | 108 | 56 | −41 | 21 | 3.90 | 0.0007 |
| R | Temporal Lobe | WM, Superior Temporal Gyrus |
13 | 108 | 55 | −42 | 15 | 3.32 | 0.003 |
| R | Temporal Lobe | Inferior Temporal Gyrus | 37 | 297 | 45 | −65 | −8 | 4.84 | 0.00007 |
| L | Temporal Lobe | Superior Temporal Gyrus | 38 | 108 | −43 | 9 | −16 | 3.52 | 0.002 |
| L | Parietal Lobe | WM, Inferior Parietal Lobe |
135 | −32 | −37 | 26 | 3.70 | 0.002 | |
| R | Occipital Lobe | Cuneus | 18 | 108 | 14 | −68 | 15 | 4.05 | 0.0005 |
| R | Occipital Lobe | Cuneus | 18 | 108 | 1 | −80 | 21 | 3.76 | 0.001 |
| L | Occipital Lobe | WM, Middle Occipital Gyrus |
243 | −34 | −82 | 2 | 4.32 | 0.0003 | |
| R | Cerebellum, Occipital Lobe |
Declive, Lingual Gyrus |
108 | 11 | −76 | −12 | 3.80 | 0.0009 | |
| R | Cerebellum | Declive | 9 | 108 | 31 | −54 | −13 | 3.33 | 0.003 |
| R | Cerebellum | Culmen | 270 | 21 | −35 | −11 | 5.36 | 0.00002 | |
| L | Limbic Lobe | Posterior Cingulate | 23 | 135 | −5 | −50 | 23 | −4.24 | 0.0003 |
| L | Thalamus | Medial Dorsal Nucleus | 135 | −4 | −10 | 13 | −4.51 | 0.0002 | |
| R | Temporal Lobe | Inferior Temporal Gyrus | 20 | 108 | 62 | −25 | −15 | −3.87 | 0.0008 |