Table 4.
Table 4A. Evaluation of candidate mediators on the association of ucMGP (per standard deviation increase) with mitral annular calcification, stratified by diabetes status
Odds Ratio | 95% CI | P Value | |
---|---|---|---|
No diabetes (n = 615) | |||
Calcium (Ca) adjusted* | 0.73 | 0.55 to 0.97 | 0.03 |
Phosphorus (Phos) adjusted* | 0.73 | 0.55 to 0.96 | 0.03 |
Fetuin-A adjusted* | 0.76 | 0.57 to 1.00 | 0.05 |
Ca + Phos + Fetuin-A adjusted* | 0.75 | 0.56 to 1.00 | 0.05 |
Diabetes (n = 221) | |||
Calcium (Ca) adjusted* | 1.85 | 1.25 to 2.73 | 0.002 |
Phosphorus (Phos) adjusted* | 1.89 | 1.28 to 2.79 | 0.001 |
Fetuin-A adjusted* | 2.12 | 1.40 to 3.23 | <0.001 |
Ca + Phos + Fetuin-A adjusted* | 2.08 | 1.36 to 3.17 | 0.001 |
Table 4B. Evaluation of candidate mediators on the association of ucMGP (per standard deviation increase) with aortic stenosis, stratified by diabetes status | |||
Odds Ratio | 95% CI | P Value | |
No diabetes (n = 587) | |||
Calcium (Ca) adjusted* | 0.86 | 0.58 to 1.30 | 0.48 |
Phosphorus (Phos) adjusted* | 0.82 | 0.55 to 1.24 | 0.35 |
Fetuin-A adjusted* | 0.90 | 0.60 to 1.36 | 0.62 |
Ca + Phos + Fetuin-A adjusted* | 0.88 | 0.59 to 1.33 | 0.55 |
Diabetes (n = 211) | |||
Calcium (Ca) adjusted* | 1.50 | 0.90 to 2.50 | 0.12 |
Phosphorus (Phos) adjusted* | 1.51 | 0.91 to 2.51 | 0.12 |
Fetuin-A adjusted* | 1.44 | 0.86 to 2.44 | 0.17 |
Ca + Phos + Fetuin-A adjusted* | 1.43 | 0.84 to 2.42 | 0.19 |
Also adjusted for age, sex, race, body mass index, hypertension, smoking, systolic blood pressure, diastolic blood pressure, albumin, total cholesterol, high density lipoprotein cholesterol, C-reactive protein, estimated glomerular filtration rate