Figure 1.
Response of optical macrosensor to glucose. (A) Calibration curve and (B) effects of chemical interferents on the calibration. Mean ± SD (n = 24) for A and mean ± SD (ncontrol = 9, nascorbic acid = 8, nuric acid= 9, nacetaminophen = 8) for B is shown. There was no statistically significant difference in response to these common interferents with p > 0.01 when compared to the control at each concentration. (C) Reversibility of the response to glucose. Percent change refers to the loss of fluorescence intensity exhibited by macrosensor when exposed to 1M glucose in PBS versus control (PBS) (ncontrol=7 and nglucose=6).