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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Clin Cancer Res. 2010 Apr 13;16(9):2580–2590. doi: 10.1158/1078-0432.CCR-09-2937

Figure 4. Sulforaphane decreased tumor size and ALDH-positive cell population in primary breast cancer xenografts.

Figure 4

NOD/SCID mice bearing SUM159 cells in fat pads as xenografts were treated with daily i.p. injection of control or 50 mg/kg sulforaphane for 2 weeks. Tumor volumes (A) and mouse body weights (B) were determined as described in “Materials and Methods”. Tumors in sulforaphane-treated mice were 50% the size of control animals at the end of drug treatment. (C) Sulforaphane decreased the percentage of ALDH-positive cells in xenograft breast tumors. (D) A set of representative flow cytometry plots. Data are presented as mean ± SD(n = 6). ALDH = aldehyde dehydrogenase.