Fig. 6. Reduced expression of hepatic cytokines and chemokines in STAT3^Hep−/− mice post CCl₄ injection.

Mice were injected with CCl₄ and then sacrificed 12 h and 24 h. A. Liver tissues were collected for real-time PCR analyses for cytokine and chemokine expression at 12 h post injection. B. Serum cytokines and chemokines. Values represent means±SD (n=5–6 in each group) *P<0.05, **P<0.01, ***P<0.001 in comparison with corresponding WT littermate groups.