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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Hepatology. 2010 May;51(5):1724–1734. doi: 10.1002/hep.23532

Fig. 7. Disruption of STAT3 in hepatocytes restores the sensitivity of STAT3Mye−/− mice to CCl4-induced liver injury.

Fig. 7

Four different lines of mice were injected with CCl4 and then sacrificed 12 h and 24 h post injection. A. H&E staining of liver tissues 24 h post CCl4 treatment. B. Serum ALT levels. C. Necrotic area in panel A was quantified. D, E. Real-time PCR analyses for MPO, CCR2, and F4/80 expression 12 h and 24 h after CCl4 injection. Values represent mean±SD (n=7–8 in each group). *P<0.05, **P<0.01, ***P<0.001 in comparison with groups as indicated.

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