Table 4.
Association of rs1333049 with recurrent myocardial infarction or cardiac death in the GRACE Genetics Study
| rs1333049 | No recurrent MI or cardiac death | Recurrent MI or cardiac death | Age- and gender-adjusted |
Multivariable-adjusteda |
||
|---|---|---|---|---|---|---|
| 2737 (93.0%) | 205 (7.0%) | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Genotypic, n (%) | ||||||
| CC | 701 (25.6%) | 55 (26.8%) | 1.39 (0.82–2.37) | 0.22 | 1.33 (0.88–2.03) | 0.18 |
| GC | 1347 (49.2%) | 113 (55.1%) | 1.69 (1.06–2.69) | 0.028 | 1.58 (1.09–2.30) | 0.016 |
| GG | 689 (25.2%) | 37 (18.0%) | Reference | Reference | ||
| Dominant, n (%) | ||||||
| CC + GC | 2048 (74.8%) | 168 (82.0%) | 1.58 (1.00–2.48) | 0.045 | 1.49 (1.03–1.98) | 0.028 |
| GG | 689 (25.2%) | 37 (18.0%) | Reference | Reference | ||
Data are analysed by a Cox proportional hazard model.
CI, confidence interval; HR, hazard ratio.
aAdjustments as in Table 4.