Partition coefficient for various double-chain anchors embedded in a membrane consisting of model DPPC, DOPC, and cholesterol. The mole fractions of the chain anchors in the liquid-order and liquid-disorder phases are xlo and xld, respectively. The number of carbons in the chain is n. The stars represent the values of the partition coefficient in the bulk lipid bilayer. (A) The temperature is 290 K. The concentrations of the lo phase are xc = 0.48, xs = 0.30, and xu = 0.22, whereas those of the ld phase are xc = 0.27, xs = 0.21, and xu = 0.52. (B) The temperature is 300 K. The concentrations of the lo phase are xc = 0.52, xs = 0.26, and xu = 0.22, whereas those of the ld phase are xc = 0.32, xs = 0.22, and xu = 0.46.