Table 6.
Nine-item National Eye Institute Visual Function Questionnaire (NEI VFQ-9) Composite Scores by Eye Disease in Women Who Participated in the Study of Osteoporotic Fractures (SOF) Year-10 Clinic Visits.
| Eye Disease | NEI VFQ: Mean ± SD (Median) | |
|---|---|---|
| Composite Score (9-item)* N=853 |
Composite Score (8-item)† N=1,237 |
|
| Overall | 92.1 ± 9.9 (95) | 89.5 ± 12.8 (94) |
| Any chronic eye disease‡ | ||
| No eye diseases in both eyes (n=360)‡ |
94.1 ± 6.2 (96) (n=259) |
93.0 ± 7.4 (95) (n=351) |
| Yes in at least one eye (n=838) | 91.1 ± 11.2 (95) (n=549) |
88.0 ± 14.3 (94) (n=811) |
| P-value§ | P=0.005 | P<0.001 |
| Bilateral chronic eye disease (n=556) | 91.2 ± 11.8 (96) (n=353) |
87.9 ± 15.2 (94) (n=534) |
| Age-related macular degeneration (AMD) | ||
| No eye diseases in both eyes (n=219)‡ |
93.7 ± 6.7 (96) (n=162) |
92.8 ± 7.6 (95) (n=213) |
| Early AMD in at least one eye (n=513) | 92.5 ± 8.9 (96) (n=343) |
89.7 ± 12.6 (94) (n=495) |
| Late AMD in at least one eye (n=42) | 79.3 ± 23.6 (88) (n=24) |
72.8 ± 26.3 (86) (n=39) |
| Difference (no vs. late AMD) | 14.4 | 20 |
| P-value§ | P=0.003 | P<0.001 |
| Bilateral early AMD (n=286) | 92.3 ± 8.7 (95) (n=181) |
89.1 ± 13.3 (94) (n=273) |
| Bilateral late AMD (n=20) | 73.4 ± 29.8 (86) (n=9) |
62.3 ± 28.7 (59) (n=17) |
| Glaucoma | ||
| No eye diseases in both eyes (n=360)‡ |
94.1 ± 6.2 (96) (n=259) |
93.0 ± 7.4 (95) (n=351) |
| Glaucoma in at least one eye (n=105) | 92.7 ± 8.2 (96) (n=54) |
85.7 ± 16.5 (93) (n=102) |
| P-value§ | P=0.609 | P<0.001 |
| Bilateral glaucoma (n=57) | 91.4 ± 9.2 (95) (n=30) |
86.7 ± 14.1 (91) (n=54) |
| Visually significant cataract | ||
| No eye diseases in both eyes (n=360)‡ |
94.1 ± 6.2 (96) (n=259) |
93.0 ± 7.4 (95) (n=351) |
| Phakia with visually significant cataract in at least one eye (n=332) |
90.9 ± 10.7 (95) (n=220) |
88.0 ± 12.8 (93) (n=323) |
| Aphakia/pseudophakia in both eyes (n=376) |
91.0 ± 12.3 (96) (n=239) |
88.0 ± 15.6 (94) (n=359) |
| P-value§ | P=0.007 | P<0.001 |
| Bilateral phakia with visually significant cataract (n=87) |
93.3 ± 7.3 (96) (n=53) |
88.4 ± 12.8 (94) (n=86) |
| Bilateral aphakia/pseudophakia or phakia with visually significant cataract (n=517) |
91.2 ± 11.8 (96) (n=330) |
88.1 ± 14.9 (94) (n=495) |
SD = Standard deviation.
*
NEI VFQ-9 9 item composite score was calculated among women who had valid responses to all 9 items.
†
NEI VFQ-9 8 item composite score was calculated among women who had valid responses to all 8 items, except for the driving item.
‡
Any chronic eye disease includes age-related macular degeneration, glaucoma, and visually significant cataract.
§
Kruskal-Wallis test.