Skip to main content
. Author manuscript; available in PMC: 2010 May 2.
Published in final edited form as: Pigment Cell Melanoma Res. 2007 Jun 28;21(5):565–578. doi: 10.1111/j.1755-148X.2008.00482.x

Figure 3.

Figure 3

Substrains exhibiting discordant coat color and iris appearances. Coat color (left column), broadbeam illumination of iris (middle column), and transilluminating view of iris (right column). (A–C) beige mice have slightly diluted coats, but irides that appear very dark. (D–F) buff mice have relatively severe dilution of coat color, but only a slight dilution of iris pigmentation evident by mild transillumination defects. The transillumination defects exhibited no discernable pattern, other than that the extent of the defects tended to increase peripherally. No influence of age was detectable. (G–I) cocoa mice have a modest dilution of coat color but strikingly hypopigmented irides (J–L) recessive yellow mice have yellow coats, but normally pigmented irides that are indistinguishable from those of normally pigmented C57BL/6J mice. All mice were homozygous for the indicated mutations and were maintained on a C57BL/6J genetic background.