Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Enzyme selectivity defined by metagenome sequence and chemical analysis. Natural products from the pat (top) and tru (bottom) pathways contain modified Cys, Ser, and Thr residues in the defined positions. y-axis: % of natural products containing these modifications. x-axis: amino acid position in cassette. Empty space above the bars denotes hypervariability: diverse amino acids occupy these positions in isolated natural products.
