Figure 2.

Structure of the central region of LTag. (a) Top view of the fitting of the atomic structure of two OBD hexamers into LTag108-627 central region. The OBDs are named as in ²⁷. The distances between domains b–e and c–f (~23-24Å) and between domains a–d (~35Å ) are represented by arrows. (b) Side view of the same fitting. Red dots indicate the location of each OBD N-terminus. The minor cathetus of the triangles depict the pitch of each OBD hexamer and the hypotenuse depicts the direction of the opening of the spiral, where is located the gap. A red square indicates the localization of the LTag108-627 central region. (c) Comparison of the parallel conformation of the wt LTag central region with the LTag108-627 central region. The left panel displays the wt central region in two colors. The green color represents the mass similar to the mutant structure and the red one, the extra mass in the wt map. The right panel shows the difference map between the central regions of the wt and mutant densities displayed as a red mesh on the mutant central domain structure.