. Author manuscript; available in PMC: 2010 May 3.

Published in final edited form as: J Neurosci Res. 2006 Aug 15;84(3):553–567. doi: 10.1002/jnr.20968

TABLE I.

D15A Expression in Conditioned Media of Schwann Cells, NIH3T3, and RN33B Cells After Viral Infection In Vitro

	No virus	Lentivirus	Adenovirus	LZRS retrovirus	MSCV retrovirus
Schwann cells	41.95 ± 10.73	3108.20 ± 641.51^*	2742.91 ± 568.76^*	1578.69 ± 288.08	2278.12 ± 541.61
Fold induction		75	66	38	55
NIH 3T3	49.36 ± 12.67	5061.83 ± 704.09	8587.98 ± 630.80^*	4570.17 ± 784.54	2612.86 ± 484.58
Fold induction		103	175	93	53
RN33B	244.72 ± 110.23^*	15273.42 ± 1529.2^*	10040.42 ± 2378.69^*	7346.98 ± 852.78^*	8590.45 ± 731.39^*
Fold induction		62	41	30	35

In Schwann cells, D15A levels in the lentiviral and adenoviral-infected cells were not different from those in the MSCV retroviral-infected group but were significantly higher than no virus and LZRS retrovirus. In NIH 3T3 cells, D15A levels in adenoviral-infected cells was significantly higher than all other groups. MSCV infected cells, D15A levels were significantly lower than all other viral infected groups. In RN33B cells, D15A levels were significantly higher than other cell types in all groups tested. D15A levels in the Lentiviral infected RN33B cells were significantly higher than all other viruses. All cells were seeded at 1 × 10⁵ cell/well. Data are expressed as mean pg D15A/24 hr/ml ± SD (n = 6).

P < 0.001.