Table 5.
Multivariate Analysis of Exercise Clinical and Echocardiographic Correlates of Exercise Capacity (METs)
| Multivariate Analysis | ||||
|---|---|---|---|---|
| Exercise Variables | B* Unstandardized (SE) | 95% CI | Bψ Standardized | p |
| Post exercise E/e'≥15 | -0.41 (0.15) | -0.71 to -0.11 | -0.04 | 0.007 |
| Heart rate increase, beats/min | 0.45 (0.02), per 10 beats/min | 0.41 to 0.51 | 0.36 | <0.0001 |
| Age, years | -0.64 (0.04), per 10 years | -0.72 to –0.57 | -0.30 | <0.0001 |
| Female gender | -1.78 (0.08) | -1.92 to –1.59 | -0.32 | <0.0001 |
| Body mass index>30 kg/m2 | -1.18 (0.09) | -1.35 to –1.01 | -0.20 | <0.0001 |
| Peak systolic blood pressure, mmHg | 0.07 (0.02), per 10 mmHg | 0.03 to 0.10 | 0.10 | 0.0001 |
| Previous/current smoker | -0.26 (0.08) | -0.41 to –0.10 | -0.05 | 0.001 |
| History of hypertension | -0.23 (0.10) | -0.43 to –0.04 | -0.03 | 0.02 |
| History of diabetes mellitus | -0.28 (0.14) | -0.54 to –0.01 | -0.03 | 0.04 |
Multivariate analysis (n=2366). Multivariate model also adjusted for ejection fraction, left atrial volume, left ventricular diastolic dimension, CAD, and medications (beta-blockers, calcium channel blockers and ACE/ARB) which were not statistically significant in the final model.
R2 = 0.54 and Intercept 10.49
*
β = Slope of the regression line for each variable and exercise capacity, expressed per unit of each variable or as outlined beside variable (unstandardized coefficient).
ψ
β= standardized slope in the same units of measure.