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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Per Med. 2010;7(2):197–204. doi: 10.2217/pme.10.5

Figure 4. Operating characteristics of the adaptive aspects of the trial.

Figure 4

The left column is for simulated trials where the true value of γ is 1.2, and the right column where the true value is 1.7. The top row displays the median and 5 and 95% percentiles of posterior distribution of γ as the patient number increases. The middle row shows the proportions of patients with k2i > 0.39. The bottom row displays the mean (solid line) and maximum (dashed line) of k2i for those patients with k2i > 0.39.

p15: 15 min after administration.