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. 2010 Jan 26;18(4):674–683. doi: 10.1038/mt.2010.2

Figure 2.

Figure 2

The T2/onc transposon vector to introduce mutations. This DNA vector contains elements designed to elicit either transcriptional activation (MSCV 5′ LTR and splice donor, SD) or inactivation [splice acceptor (SA) and polyadenylation signal, pA] when landing within/near an endogenous gene. IRL and IRR denote the left and right inverted terminal repeats of the SB transposon, respectively. MSCV, murine stem cell virus.