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. 2009 Oct 28;29(43):13543–13556. doi: 10.1523/JNEUROSCI.4144-09.2009

Figure 8.

Figure 8.

Simvastatin and pravastatin inhibit mRNA expression of GFAP and CD11b in ventral midbrain of MPTP-intoxicated mice. Mice receiving simvastatin and pravastatin (1 mg · kg body weight−1 · d−1) from 3 h after the last injection of MPTP were killed 24 h after the last injection of MPTP. The mRNA expression of GFAP and CD11b was analyzed by semiquantitative RT-PCR (A) and quantitative real-time PCR (B). Data are means + SEM of five mice per group. ap < 0.0001 versus saline group; bp < 0.0001 versus the MPTP group.