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TUNEL staining in splenic tissues in young (3-months-old, A-B) or aged (24-months-old, C-D) rats at 4 h after normal saline (Sham) or LPS (LPS) injection. The TUNEL positive cells were mainly located in the red pulb of the spleen, and aging animals showed a marked increase in the number of TUNEL positive cells both in Sham (C) and LPS (D) groups. Original magnification: 200 X.
