Figure 1. Comparison of the genomic locations of heterozygous cSNPs exhibiting imbalanced allelic expression in mRNA of twins 041896-001 and -101.
a, b, Allelic imbalance for 041896-001 (a) and 041896-101 (b) was detected in cSNPs called by ≥10 gDNA reads with Q ≥ 20 and where 20–80% of uniquely aligning gDNA reads called the SNP, together with detection in ≥10 mRNA reads with Q ≥ 20. Out of 14,461 heterozygous cSNPs, 268 (1.9%) showed significant allelic imbalance in expression (P < 10-7), of which 153 (57%) were of the same magnitude and direction in both subjects. TCRVB is the T cell receptor beta locus, V (variable) segment, locus symbol TRB@. WDR40B is also known as DCAF12L1.