Table 2.

The relative change of diffusion contrasts between lesions at 3 days, 30 days, and uninjured contralateral white matter.

Contrast	Lesion at 3 Days		Lesion at 30 Days		Lesion at 30 Days
	Vs. Uninjured WM		Vs. Uninjured WM		vs. Lesion at 3 Days
	Change (%)	p-value	Change (%)	p-value	Change (%)	p-value
FA	−16 ± 5	* < 0.0001	−39 ± 8	* < 0.0001	−31 ± 10	* < 0.0001
D⊥	30 ± 21	* 0.005	89 ± 26	* < 0.0001	66 ± 23	* < 0.0001
D∥	−34 ± 9	* < 0.0001	−33 ± 21	* 0.002	−5 ± 16	0.4
MD	−22 ± 8	* < 0.0001	−5 ± 18	0.5	17 ± 15	0.02
FWHM⊥	10 ± 8	* 0.009	17 ± 9	* 0.001	7 ± 8	0.05
RMSD⊥	14 ± 9	* 0.002	45 ± 13	* < 0.0001	35 ± 12	* < 0.0001
PZERO⊥	−13 ± 7	* 0.001	−25 ± 10	* < 0.0001	−17 ± 8	* 0.0004
KE⊥	−18 ± 9	* 0.0007	−30 ± 20	* 0.004	−13 ± 10	* 0.0091
FWHM∥	−32 ± 13	* < 0.0001	−41 ± 29	* 0.004	−24 ± 14	* 0.002
RMSD∥	−18 ± 6	* < 0.0001	−15 ± 9	* 0.003	0 ± 10	0.9
PZERO∥	35 ± 13	* < 0.0001	41 ± 23	* 0.001	16 ± 14	0.02
KE∥	106 ± 45	* < 0.0001	103 ± 69	* 0.001	24 ± 31	0.08
$\stackrel{‒}{\mathrm{KE}}$	−8 ± 8	0.03	−17 ± 16	0.02	−6 ± 10	0.2

Positive (negative) values denote an increase (decrease) in the diffusion measure relative to the uninjured contralateral WM (columns 1 and 2) or relative to the lesion 3 days after axotomy (column 3).

^*denotes significant difference (p < 0.01) for the ROI analysis presented in Figures 2B, 3B and 4B.