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. 2009 Dec 18;16(3):795–805. doi: 10.1089/ten.tea.2009.0370

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Copyright 2010, Mary Ann Liebert, Inc.

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FIG. 2. — Vessel density in DIP chamber constructs. (a) In E-circulated constructs, endothelial (brown) sprouts appear to extend out into the matrix and, in some instances, inosculate other vessels (arrows). Within E+I-circulated constructs (b), many patent microvessels were found, but little sprouting was evident (arrows). E-circulated constructs contained significantly more microvessels (c) and fewer patent microvessels (d) than E+I-circulated sections (^#p < 0.0001). (e) If lumen number was normalized to construct cross section, there was no significant difference between E-circulated and E+I-circulated samples (p = 0.93). All calculated values are presented as mean ± standard error of the mean (s.e.m). The scale bar for (a) and (b) is 200 μm. Color images available online at www.liebertonline.com/ten.

FIG. 2. — Vessel density in DIP chamber constructs. (a) In E-circulated constructs, endothelial (brown) sprouts appear to extend out into the matrix and, in some instances, inosculate other vessels (arrows). Within E+I-circulated constructs (b), many patent microvessels were found, but little sprouting was evident (arrows). E-circulated constructs contained significantly more microvessels (c) and fewer patent microvessels (d) than E+I-circulated sections (^#p < 0.0001). (e) If lumen number was normalized to construct cross section, there was no significant difference between E-circulated and E+I-circulated samples (p = 0.93). All calculated values are presented as mean ± standard error of the mean (s.e.m). The scale bar for (a) and (b) is 200 μm. Color images available online at www.liebertonline.com/ten.