Table 2.
Selected genes from the overlap between those overexpressed in PTHrP−/− as compared to WT mammary buds and those overexpressed in WT ventral skin as compared to WT mammary buds.
| Extracellular Matrix | Transcription Factors | Growth Factor Signaling |
|---|---|---|
| Collagen, Type IX, alpha 1 (Col9a1) |
Basic transcription factor 3 (Btf3) |
Neuropilin (Nrp) |
| EGF-like-domain, multiple 6 (Egfl6) |
Enhancer of yellow 2 homolog (Eny2) |
Wnt inhibitory factor 1 (Wif1) |
| Matrilin 2 (Matn2) | Down-regulator of transcription 1 (Dr1) |
WNT1 inducible signaling pathway protein 1 (Wisp1) |
| Reversion-inducing- cyteine-rich protein with kazal motifs (Reck) |
Activating transcription factor 4 (Atf4) |
Nephroblastoma overexpressed gene (Nov, CCN3) |
| Nidogen 1 (Nid1) | Transcription factor 4 (Tcf4) |
Kit oncogene (c-Kit) |
| BSpondin 1 (Spon1) | Nuclear DNA binding protein (C1d) |
Platelet derived growth factor receptor-beta (Pdgfrb) |
| Thrombospondin 1 (Thbs1) | Friend leukemia integration 1 (Fli1) |
Patched homolog 1 (Ptch1) |
| Epidermal growth factor- containing fibulin-like extracellular matrix protein 1 (Efemp1) |
Minichromosome maintenance deficient 6 (Mcm6) |
|
| Asporin (Aspn) |