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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Immunol. 2010 Mar 1;184(7):3424–3432. doi: 10.4049/jimmunol.0904057

Figure 2. IFNγ production by NK cells from B10.RIII mice is not influenced by a known region of genetic contamination.

Figure 2

IFNγ production by Ly49A+ NK cells from mice expressing RIII- or C57BL/6 (B6)-derived regions on chromosome 10 or at the MHC locus. B10.RIII mice were crossed with B6 mice, and the F2 pups were typed by microsatellite analysis to select for mice homozygous for the RIII- or B6-derived segments on chromosome 10 and chromosome 17, as indicated. Bars represent average frequency ± SD of IFNγ production by naïve Ly49A+ NK cells (NK1.1+ CD3− CD19−) incubated with plate-bound anti-NK1.1 antibody (2 µg PK136). N=9 per group. Pooled results from three independent experiments. *: p<0.05; ***: p<0.001