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Immunostaining of tumors from Figure 2 for endothelial cells (CD31; red) or pericytes (α-smooth muscle actin; α-SMA; green). Numbers in parentheses are as in Figure 2. Percentage of endothelial cells associated with pericytes were calculated and shown on right. Note that pre-IR tumors showed the percent endothelial cells with pericyte coverage to be significantly lower than other groups (p < 0.001).
