Table 3.
Tumors | BRAF mutant or wild-type | BRAF mutant | ||||
---|---|---|---|---|---|---|
Cases | Controls | OR (95% CI) |
Cases | Controls | OR (95% CI) | |
MC1R consensus |
41 | 40 | reference | 21 | 22 | reference |
1 MC1R variant |
26 | 26 | 0.976 (0.486 to 1.958) |
8 | 8 | 1.048 (0.3324 to 3.302) |
≥ 2 MC1R variants |
7 | 8 | 0.854 (0.283 to 2.575) |
3 | 2 | 1.571 (0.2382 to 10.3653) |
total | 74 | 74 | p = 0.961* | 32 | 32 | p = 0.894* |
Given are odds ratios for any BRAF mutation status and for BRAF mutant cases only, depending on the number of MC1R variants compared to the matched control cohort.
Pearson chi-square test.