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(a) Mechanism of polymersome-mediated cytosolic delivery. (b) Primary human dermal fibroblast (HDF) exposed to Rhodamine-loaded (red) polymersomes imaged at different focal levels (0 µm, 5 µm, 10 µm) by confocal laser scanning microscopy (40x lens, bar 0.02 mm) and compared to untreated cells. The cell lysosomes and DNA were also stained using yellow Lysotracker and green SYTO-9, respectively. Figure bar 20 µm.
