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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Mol Immunol. 2010 Jan 29;47(6):1244–1254. doi: 10.1016/j.molimm.2009.12.013

Figure 1.

Figure 1

β-AR modulation of LPS initiated inflammatory mediators. Representative series of antibody array membranes for specific inflammatory cytokines (see Table 1) incubated with conditioned media from THP-1 cells treated with A – complete media only, B – 30 ng/mL LPS, C – 0.1 μM Iso or D – 30 ng/mL LPS plus 0.1 μM Iso as outlined in the “Materials and Methods”. There was a qualitative increase in the amount of soluble IL-1β (dashed lines) along with decreases in TNF-α (solid lines) from cells incubated with Iso plus LPS when compared to LPS alone (n = 3). There were no detectable amounts of soluble IL-1β or TNF-α from membranes incubated with complete media alone or Iso only. In addition, no consequential changes in the levels for other inflammatory cytokines were observed between the different treatment conditions.