Figure 7. Deletion of pafr reduces tactile allodynia.

While wild-type mice with an L5 nerve injury showed a progressively decreased paw withdrawal threshold, pafr ^−/− mice showed an attenuation of the decrease in paw withdrawal threshold after nerve injury. **p<0.01, ***p<0.001 compared with the threshold of wild-type mice on day 0. ††p<0.01 compared with the threshold of pafr ^−/− mice on day 0. #p<0.05, ##p<0.01 compared with the threshold of the wild-type mice at each time point. All data are presented as mean ± SEM of six to eight animals.