Table 2.
Minor allele frequencies and Hardy-Weinberg equilibrium for tested SNPs
| Gene | rs# | Allele frequency |
HWE |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Allele | AA | CAU | HAN | MA | AA | CAU | HAN | MA | ||
|
BSND |
rs5774206 | G | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| rs1003767 | A | 0.37 | 0.71 | 0.35 | 0.53 | 1.00 | 0.19 | 1.00 | 0.01 | |
| rs6682884 | C | 0.42 | 0.41 | 0.31 | 0.16 | 0.24 | 0.61 | 0.17 | 0.68 | |
| rs2864124 | C | 0.43 | 0.42 | 0.31 | 0.18 | 0.22 | 0.26 | 0.23 | <0.001 | |
| rs943645 | T | 0.41 | 0.40 | 0.28 | 0.14 | 0.44 | 0.64 | 0.24 | 1.00 | |
| rs17111474 | T | 0.39 | 0.39 | 0.41 | 0.70 | 0.22 | 1.00 | 0.28 | 0.96 | |
| rs2479398 | G | 0.09 | 0.13 | 0.04 | 0.04 | 0.93 | 0.52 | 1.00 | 0.26 | |
| rs2495506 | T | 0.18 | 0.29 | 0.57 | 0.44 | 0.09 | 1.00 | 1.00 | 0.27 | |
|
CLCNKA_B |
rs1048302 | A | 0.20 | 0.29 | 0.04 | 0.40 | 1.00 | 0.18 | 0.17 | 1.00 |
| rs1739840 | A | 0.21 | 0.40 | 0.20 | 0.56 | 1.00 | 0.17 | 0.35 | 0.80 | |
| rs1763597 | G | 0.23 | 0.40 | 0.20 | 0.57 | 0.75 | 0.19 | 0.43 | 0.94 | |
| rs945425 | T | 0.20 | 0.30 | 0.05 | 0.40 | 1.00 | 0.32 | 0.27 | 0.43 | |
| rs2003943 | C | 0.15 | 0.33 | 0.60 | 0.26 | 0.38 | 0.31 | 1.00 | 1.00 | |
| rs6604910 | C | 0.31 | 0.67 | 0.73 | 0.77 | 0.77 | 0.45 | 0.76 | 0.73 | |
| rs2050522 | T | 0.33 | 0.95 | 1.00 | 0.93 | <0.001 | 0.01 | 1.00 | 1.00 | |
| rs1414499 | C | 0.39 | 0.51 | 0.02 | 0.46 | 0.80 | 0.52 | 1.00 | 0.91 | |
| NEDD4L | rs1942563 | G | 0.28 | 0.15 | 0.00 | 0.12 | 0.21 | 1.00 | 1.00 | 0.59 |
| rs4461163 | G | 0.18 | 0.15 | 0.00 | 0.11 | 0.44 | 0.68 | 1.00 | 0.59 | |
| rs1977948 | G | 0.27 | 0.16 | 0.00 | 0.13 | 0.77 | 1.00 | 1.00 | 0.62 | |
| rs878396 | A | 0.25 | 0.21 | 0.22 | 0.30 | 0.56 | 0.34 | 0.10 | 0.18 | |
| rs6566942 | G | 0.40 | 0.22 | 0.44 | 0.10 | 0.66 | 0.35 | 0.14 | 0.20 | |
| rs4340401 | T | 0.38 | 0.22 | 0.44 | 0.12 | 0.64 | 0.54 | 0.13 | 1.00 | |
| rs1008899 | A | 0.17 | 0.35 | 0.50 | 0.30 | 0.66 | 0.58 | 0.82 | 0.10 | |
| rs4941366 | G | 0.34 | 0.65 | 0.35 | 0.58 | 0.62 | 0.64 | 1.00 | 0.53 | |
| rs513563 | T | 0.34 | 0.57 | 0.35 | 0.52 | 0.14 | 0.08 | 0.81 | 0.82 | |
| rs522155 | T | 0.36 | 0.61 | 0.45 | 0.60 | 0.34 | 0.05 | 0.83 | 0.23 | |
| rs192659 | G | 0.42 | 0.38 | 0.49 | 0.36 | 0.82 | 0.12 | 0.83 | 0.64 | |
| rs158866 | T | 0.24 | 0.52 | 0.52 | 0.46 | 0.35 | 1.00 | 0.28 | 0.50 | |
| rs158857 | G | 0.40 | 0.49 | 0.19 | 0.47 | 0.77 | 0.62 | 0.10 | 0.04 | |
| rs11152064 | C | 0.15 | 0.24 | 0.29 | 0.30 | 0.02 | 0.34 | 0.26 | 0.41 | |
| rs4941378 | C | 0.49 | 0.40 | 0.34 | 0.40 | 0.53 | 0.13 | 0.47 | 0.07 | |
| rs17064701 | C | 0.11 | 0.00 | 0.00 | 0.02 | 0.59 | 1.00 | 1.00 | 0.03 | |
| rs11664416 | C | 0.18 | 0.15 | 0.02 | 0.06 | 0.45 | 0.06 | 1.00 | 1.00 | |
| rs8089678 | G | 0.38 | 0.38 | 0.25 | 0.31 | 0.64 | 1.00 | 0.77 | 1.00 | |
| rs9675944 | G | 0.39 | 0.65 | 0.74 | 0.63 | 0.16 | 0.81 | 1.00 | 0.09 | |
| rs2075405 | G | 0.39 | 0.26 | 0.21 | 0.27 | 1.00 | 1.00 | 0.67 | 0.77 | |
| rs4940684 | A | 0.34 | 0.62 | 0.62 | 0.61 | 0.46 | <0.001 | 0.65 | 0.16 | |
AA = African Americans; CAU = Caucasians; HAN = Han Chinese; MA = Mexican Americans.