Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Association of PGE2 receptors with G-protein coupled receptors. (i) EP2R and EP4R activate adenylyl cyclase (AC) and cyclic AMP (cAMP)-dependent protein kinase A (PKA) or PKA-independent EPAC (exchange protein directly activated by cAMP) signaling. (ii) EP3R inhibits the synthesis of cAMP. (iii) EP1R activates Ca2+ and possibly (hashed line) protein kinase C (PKC) signaling.
