Table 3.
Clusters of significant brain response within the fusiform gyrus search region for object naming vs. passive viewing
| Direction of response | Hemisphere | Subregion (Brodmann’s area) | Volume (mm3) | Coordinates of maximum intensity voxel | t or F-score for maximum intensity voxel | Eta-squared (Mean±SEM) |
|---|---|---|---|---|---|---|
| APOE ε3 adults | ||||||
| Name > View | Ŧ ą L | C1. Medial fusiform gyrus (37) | 768 | 22L, 57P, 4I | 8.9 | 0.56±0.04 |
| APOE ε4 adults | ||||||
| Name > View | L | C1. Lateral posterior fusiform gyrus (37) | 1024 | 34L, 63P, 12I | 4.6 | 0.45±0.03 |
| R | C2. Medial fusiform gyrus (37) | 640 | 26R, 53P, 12I | 4.1 | 0.48±0.03 | |
| ą L | C3. Medial fusiform gyrus | 512 | 26L, 45P, 12I | 4.6 | 0.49±0.04 | |
| Main Effect of Group | ||||||
| APOE ε4 > APOE ε3 | R | C1. Medial fusiform gyrus (37) | 448 | 34R, 53P, 12I | 6.3 | 0.58±0.02 |
Clusters shown survived our cluster threshold alpha-protection procedure (p < 0.05, volume > 448 mm3, whole brain p < 0.05; see text for details). Note: L = left, R = right, A = anterior, P = posterior, S = superior, C = cluster.
ą
= brain response negatively correlated with naming accuracy performance at trend level (r’s >0.38)
Ŧ
= brain response positively correlated with naming response time performance at trend level (r’s >0.38)