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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Neurobiol Dis. 2010 Mar 6;38(3):405–413. doi: 10.1016/j.nbd.2010.02.013

Figure 1. ATP upregulates NPY expression in adult mouse OE via P2 purinergic receptor activation.

Figure 1

Mice were instilled with vehicle or P2 purinergic receptor antagonist PPADS (200 μmoles/kg) prior to intranasal instillation of vehicle or ATP (400 nmoles/kg). 20 hrs later, OE tissue was collected and assayed for NPY levels by enzyme immunoassay. n = 5, 4, 4, 3 animals each treatment.*, p<0.05 v. vehicle/saline group. #, p<0.05 v. vehicle/ATP group (two-way ANOVA followed by Bonferroni post-hoc test).