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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Brain Res Rev. 2010 Jan 4;63(1-2):72–82. doi: 10.1016/j.brainresrev.2009.12.006

Figure 5. A schematic diagram showing the NG2 cell lineage.

Figure 5

NG2 cells originate from NG2−/PDGFRα− cells in the germinal zone and acquire NG2 expression as they migrate to their destination. They have the ability to self-renew and generate oligodendrocytes at all ages. NG2 cells in the immature brain also generate a subpopulation of protoplasmic astrocytes. The neuronal fate of NG2 cells is still debated.