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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Int J Biochem Cell Biol. 2010 Feb 23;42(6):965–974. doi: 10.1016/j.biocel.2010.02.009

Figure 2. Hyperglycemia triggers dorsal and lateral filopodial-like projections in SMCs.

Figure 2

Electron micrographs of adherent SMCs cultured in euglycemic (5 mM) or hyperglycemic (25 mM) conditions with the indicated inhibitors. Inhibitors used were as follows: PKCβ(3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione, 5nM), anti-β3 antibody (10µg/ml), control antibody (10µg/ml). The photomicrographs are representative of results obtained in five experiments. The white arrow head (→) points to the lateral filapodia and black arrow head(→) points to the dorsal filapodia. Bar denotes 2µm.