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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Int J Biochem Cell Biol. 2010 Feb 23;42(6):965–974. doi: 10.1016/j.biocel.2010.02.009

Table 1.

Hyperglycemia promotes the development of intimal hyperplasia in an integrin β3-dependent manner.

Genotype Number of
vessels		 Intima (µm2) Media (µm2) I/M Ratio Lumen (µm2)
WT (DM) 10 21561 ± 1266 9784 ± 1736 2.40 ± 0.30 6501 ± 1059
Itgβ3−/− (DM) 10 15000 ± 1378 15600 ± 2182 1.00 ± 0.08 17400 ± 1288
WT(DM) vs
Itgβ3−/−(DM)		 P = 0.008 P = 0.070 P = 0.002 P = 0.001
WT(ctl) 16 14600±2800 9400 ±600 1.45±0.2 21 000±3100
Itgβ3−/−(ctl) 16 12700±1000 9000±800 1.3±0.1 24 600 ±2700
WT(ctl) vs
Itgβ3−/−(ctl)		 P = 0.75 P = 0.064 P = 0.60 P = 0.70

Areas (mean ± SE) for intima, media, and lumen of wild-type (WT) or Itgβ3−/− mice are provided. For comparison, control (ctl) values from an earlier publication are included (Smyth et al., 2001).