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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Int J Cancer. 2010 Jul 1;127(1):32–42. doi: 10.1002/ijc.25029

Figure 7.

Figure 7

Cell growth inhibition by sodium selenite was JNK1 dependent in colon cancer cells HCT116. Knockdown of JNK1 by siRNA abrogated sodium selenite-mediated inhibition of cell growth (A) and suppression of the expression of β-catenin signaling pathway (B) (48 h). si-GFP was a small interfering RNA targeting human green fluorescence protein (GFP) and was used as mock control; si-JNK1 was a small interfering RNA targeting human JNK1. The knockdown efficiency was confirmed by western blotting. These experiments were triplicated independently. The image signal was quantified and normalized to β-actin. The ratio was presented right below the image. (* p<0.01, compared to the “0”)