Figure 1.
Timeline showing contractile period of engineered cardiac tissue containing Matrigel (outlined) or porcine SIS gel (filled). Engineered tissue constructs began contracting on day 3 or day 4 and continued for up to 10 days. One construct from each group was still contracting at the time of snap-freezing on day 13. No significant differences were observed between constructs containing Matrigel (M1–3) or SIS gel (S1–3) for the following parameters: the time between cell seeding and initial contractions; the duration of contractions; and the time between cell seeding and final contractions.