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. Author manuscript; available in PMC: 2011 May 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Jan 25;245(1):36–46. doi: 10.1016/j.taap.2010.01.008

Fig. 5.

Fig. 5

Effects of loss of Cav-1 on acetaminophen metabolism. Serum was collected 30 min after administration of acetaminophen to wild type and Cav-1−/− mice and analyzed by HPLC for the presence of APAP, APAP-glucuronide (-gluc), and APAP-sulfate (-sulf) metabolites, with retention times of 15, 9.1 and 8 min respectively; IS, internal standard. One representative chromatogram from 3 mice/strain is shown.