Table5.

Brain shape and size differences of registering separately the 7 additional Chinese subjects into the ICBM152 and the Chinese_56 atlas spaces

Measurement (Mean±S.D.)	Original brains	Registered to ICBM152(12P)	Registered to Chinese_56(12P)	P-value
				P1	P2
AC-PC (mm)	25.52±1.53	28.57±1.72	26.79±1.34	1.74E-03*	0.03
Length (mm)	157.99±4.25	172.14±6.20	167.36±1.88	2.83E-03*	7.98E-04*
Width (mm)	141.44±3.69	140.57±2.76	144.46±2.97	0.42	0.02
Height (mm)	108.80±5.14	127.00±4.16	109.10±2.90	1.45E-04*	0.87
W/L	0.90±0.04	0.82±0.03	0.86±0.02	7.40E-03*	0.05
H/L	0.69±0.05	0.74±0.04	0.66±0.02	0.07	0.06
H/W	0.77±0.03	0.90±0.03	0.76±0.03	2.89E-05*	0.25

^*P < 0.01

Seven new Chinese brain MRI volumes were aligned separately to both the Chinese brain template (Chinese_56) and the ICBM152 atlas using a 12-parameter transformation. A quantitative assessment of the brain global features was performed. P1 was the statistical significacet for the measured values of original brains and the brains registering to the ICBM152 atlas. Similarly, P2 was the statistical significance for the measured values of original brains and the brains registering to the Chinese_56. These results show that more deformation was required in brain shape and size when Oriental brains are registered to the ICBM152 template using a 12-parameter transformation.