TABLE 1.

The electrophysiological parameters of the ANF model

Parameter	Value			Reference
Node of Ranvier
Resistance, Rm	166.2 kΩ mm2			Mino et al. 2004
Capacitance, Cm	0.5125 nF/mm2			Mino et al. 2004
Internode				Tasaki 1955
Resistance, rm	a			Mino et al. 2004; Cartee 2006
Capacitance, cm
Na channel				Matsuoka et al. 2001
Nernst potential, ENa	66 mV
Density, ρNa	80/μm2b			Mino et al. 2004
Conductance, γNa	22.65 pS
K channel
Nernst potential, EK	−88 mV
Density, ρK	45/μm2b
Conductance, γK	50.0 pS
Na+ gating kineticsc	A	B	C	Schwarz and Eikhof 1987
αm	1.872	25.41	6.06
βm	−3.793	21.001	9.41	Matsuoka et al. 2001
αh	−0.549	−27.74	9.06
βh	22.57	56	12.5
K+ gating kineticsc
αn	0.129	35	10
βn	−0.324	35	10
Axoplasmic resistance, Ra	6378 Ω mm			Mino et al. 2004
Resting potential, Erest	−78 mV			Neumcke and Stämpfli 1982
Extracellular resistivity, ρe	0.3 kΩ cm			McNeal 1976

^aε₀ is the permittivity of free space (8.854 × 10⁻¹² F/m), ε_l is the myelin dielectric constant (1.27), l_ε is the length of compartment one of the nine sub-units of the internode, D is the outer myelinated fiber diameter, d is the unmyelinated (inner) fiber diameter, and ρ_m is the internodal resistivity (29.26 GΩ mm)

^bModified from ρ_Na = 27/μm² and ρ_Na = 10.6/μm² for producing absolute refractory period = 0.41 ms

^c.