Table 4.
Change in mean body weight
| Treatment mg/kg PO | Mean body weight grams ± SEM | |||||||
|---|---|---|---|---|---|---|---|---|
| Day 0 | % | Day 12 | % | Day 13 | % | Day 14 | % | |
| Vehicle water + DSS | 345 ± 4.7 | 100 ± 0 | 400 ± 5.4 | 116 ± 2.1 | 403 ± 5.0 | 117 ± 1.9 | 403 ± 5.0 | 117 ± 1.9 |
| AMB 37.7 + DSS | 349 ± 5.4 | 100 ± 0 | 403 ± 6.0 | 115 ± 0.9 | 406 ± 5.4 | 116 ± 0.9 | 402 ± 3.8 | 115 ± 1.5 |
| AMB 377.1 kg +DSS | 349 ± 5.1 | 100 ± 0 | 405 ± 5.1 | 116 ± 1.8 | 408 ± 5.9 | 117 ± 2.2 | 408 ± 6.4 | 117 ± 2.0 |
| AdvAMB 57.4 + DSS | 348 ± 5.1 | 100 ± 0 | 392 ± 6.6 | 113 ± 0.6 | 396 ± 7.1 | 114 ± 1.0 | 399 ± 7.4 | 115 ± 0.9 |
| AdvAMB 574.3 +% DSS | 344 ± 5.1 | 100 ± 0 | 393 ± 6.1 | 114 ± 1.3 | 398 ± 5.7 | 116 ± 1.4 | 397 ± 7.4 | 115 ± 1.7 |
| Vehicle water + water | 347 ± 2.9 | 100 ± 0 | 404 ± 5.3 | 117 ± 1.1 | 405 ± 6.8 | 117 ± 1.6 | 405 ± 6.8 | 117 ± 1.6 |
| AMB 37.7 + water | 348 ± 4.7 | 100 ± 0 | 409 ± 9.4 | 117 ± 1.9 | 413 ± 9.4 | 119 ± 1.8 | 414 ± 9.1 | 119 ± 1.8 |
| AMB 377.1 + water | 349 ± 4.5 | 100 ± 0 | 403 ± 6.9 | 115 ± 1.5 | 404 ± 7.2 | 116 ± 1.5 | 406 ± 7.5 | 117 ± 1.6 |
| AdvAMB 57.4 + water | 346 ± 4.3 | 100. ± 0 | 403 ± 4.2 | 117 ± 2.0 | 407 ± 4.3 | 118 ± 1.9 | 409 ± 4.3 | 118 ± 1.7 |
| AdvAMB 574.3 + water | 348 ± 5.5 | 100 ± 0 | 408 ± 10 | 117 ± 1.7 | 412 ± 11 | 118 ± 1.8 | 417 ± 11 | 120 ± 1.9 |
Change in rat body weight (mean ± SEM) and mean ± SEM percent of baseline weights. Percentage body weight was calculated using day 0 weight as the denominator