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. Author manuscript; available in PMC: 2010 May 4.
Published in final edited form as: Chemistry. 2009 Dec 7;15(47):12978–12992. doi: 10.1002/chem.200902172

Table 13.

Resolution of 2-aryl allylic alcohols.

graphic file with name nihms194467u12.jpg
entry alcohol major enantiomer conditions[a] time conv.[b] alcohol ee[c] s
1 R = H A 7 h 57% 99% 35
2 B 1.5 h 53% 99% 89
3 D 10 h 56% 99% 47
4 R = Me B 3.5 h 58% 99% 31
5 C 11 h 58% 99% 28
6 graphic file with name nihms194467t26.jpg R = OMe D 10 h 56% 99% 39
7 A 31 h 58% 99% 30
8 B 1.5 h 54% 97% 46
9 C 24 h 55% 92% 23
10 R = F A 10 h 57% 99% 33
11 B 3.5 h 60% 99% 24
12 C 11 h 58% 99% 30
13 R = CF3 A 10 h 59% 99% 26
14 C 10 h 57% 94% 21
15 D 10 h 59% 99% 26
16 graphic file with name nihms194467t27.jpg A 10 h 59% 99% 28
17 B 1.5 h 53% 94% 36
18 D 10 h 56% 99% 45
19 graphic file with name nihms194467t28.jpg A 24 h 54% 99% 59
20 C 10 h 59% 99% 25
21 D 6 h 57% 97% 27
22 graphic file with name nihms194467t29.jpg B 10 h 64% 99% 19
23 C 72 h 57% 96% 23
24 D 42.5 h 57% 98% 27
25 graphic file with name nihms194467t30.jpg A 17 h 52% 99% 122
26 B 3 h 57% 97% 27
27 C 24 h 55% 97% 33
[a–c]

See Table 10 footnotes.