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. 1998 Aug 8;317(7155):376–379. doi: 10.1136/bmj.317.7155.376

Table 4.

 Effects and costs of three screening policies for breast cancer

Current programme Extension to age 69 Two year interval
Effectiveness (no discounting)
Reduction in mortality (%)* 12.8 16.4 15.3
Deaths prevented/year* 147 188 175
Total deaths prevented  4 079  5 311  4 880
Life years gained 66 187 78 221 81 322
Costs (£m) (6% discounted)
Screening 26.8 34.7 36.9
Diagnosis (screening) 17.4 21.1 19.7
Diagnosis (outside screening) −11.1  −14.1  −12.9 
Primary treatment  6.2  9.1  7.1
Adjuvant therapy −1.5 −2.1 −1.8
Follow up  2.9  4.0  3.5
Advanced disease −9.8 −13.1 −11.8 
Total 30.9 39.6 40.6
Effectiveness (6% discounted)
Deaths prevented  1 229  1 636  1 457
Life years gained 12 251 15 161 14 987
Cost effectiveness (6% discounted)
Cost per death prevented (£) 25 142 24 205 27 865
Cost per life year gained (£)  2 522  2 611  2 709
Marginal cost effectiveness/life year gained (£)  2 990  3 545
*

In a steady state.