. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Metab Brain Dis. 2009 Oct 21;24(4):525–539. doi: 10.1007/s11011-009-9161-6

Table 2.

Dopamine cell count in lesioned and non-lesioned substantia nigra pars compacta of prenatally stressed and non-stressed rats

Rat	Lesionedhemisphere		Non-lesionedhemisphere
	Runners	Non-runners	Runners	Non-runners
Non-stressed	9.31±0.96	8.20±0.48	19.31±0.97^b	27.67±0.56
Prenatally stressed	10.92±0.57	5.33±0.18^a	27.54±0.51	28.61±1.42

Two-way ANOVA of dopamine cell count in the left (lesioned) substantia nigra pars compacta of prenatally stressed and non-stressed rats revealed a significant effect of exercise (F(1,32)=29.4, P<0.0001) and a significant interaction between prenatal stress and exercise (F(1,32)=13.1, P<0.001). Post-hoc Tukey HSD test revealed significant difference between dopamine cell count in the left (lesioned) substantia nigra pars compacta of stressed runners and stressed non-runners (P<0.0005). Stressed non-runner dopamine cell counts in the left (lesioned) substantia nigra were lower than non-stressed non-runners (P<0.05). Two-way ANOVA of dopamine cell count in the right (non-lesioned) substantia nigra pars compacta of prenatally stressed and non-stressed rats revealed significant effects of stress (F(1,32)= 23.7, P<0.0001) and exercise (F(1,32)=25.0, P<0.0001) and a significant interaction between stress and exercise (F(1,32)=14.9, P<0.001). Results are mean ± SEM (n=9)

Significantly lower than other lesioned substantia nigra TH-positive cell counts (Tukey HSD post-hoc test, P<0.05)

Significantly lower than other non-lesioned substantia nigra TH-positive cell counts (Tukey HSD post-hoc test, P<0.0005)