Figure 2.
Pol β (0.1 nM) and dTTP (50 μM) mediated extension of Ape1 incised C2-AP (5′-32P-11, starting material) in the (A) absence or (B) presence of FEN1 (1 nM). Each data point is the average of 3 independent measurements ± standard deviation.
Pol β (0.1 nM) and dTTP (50 μM) mediated extension of Ape1 incised C2-AP (5′-32P-11, starting material) in the (A) absence or (B) presence of FEN1 (1 nM). Each data point is the average of 3 independent measurements ± standard deviation.