Table 2.
Amphotericin B in glucose 5% | Amphotericin B in intralipid 20% | |
---|---|---|
Dose (mean) (SD): | ||
Absolute (mg/day) | 43.8 (9.0) | 47.7 (9.0) |
Relative (mg/kg/day) | 0.7 (0.1) | 0.7 (0.1) |
Cumulative (mg) | 513.3 (260.0) | 489.0 (320.0) |
Treatment duration (mean) (SD): | ||
Days on study | 15.8 (9.1) | 13.8 (8.8) |
Treatment days | 11.3 (5.2) | 9.9 (5.1) |
Incidence of toxicity related schedule modifications (No of patients): | ||
Prolongation of infusion duration | 17 | 15 |
Dose reduction | 6 | 4 |