Table 3.
Variable | Amphotericin B in glucose 5% | Amphotericin B in intralipid 20% |
---|---|---|
Serum creatinine concentration (mean) (SD; normal range 50-80 μmol/l) | ||
Day: | ||
0 | 75.1 (23.7) | 76.5 (27.4) |
4 | 94.6 (43.7) | 99.3 (67.6) |
8 | 85.1 (22.8) | 90.3 (25.7) |
Last | 105.9 (73.6) | 109.1 (72.2) |
Mean | 85.6 (31.3) | 89.4 (38.8) |
Maximum | 117.1 (65.5) | 130.6 (76.7) |
Creatinine clearance (mean) (SD; normal range 80-170 ml/min) | ||
Day: | ||
0 | 116.0 (40.5) | 120.6 (42.4) |
4 | 103.5 (45.2) | 104.7 (48.8) |
8 | 99.1 (43.7) | 96.3 (35.9) |